APJ receptor agonist 5
Product Specifications
CAS Number
2135514-20-2
Target
Others, Apelin receptor
Related Pathways
Others, GPCR/G Protein
Bioactivity
APJ receptor agonist 5 (compound 3) is a potent and orally active apelin receptor (APJ) agonist (EC 50: 0.4 nM) with excellent pharmacokinetic profiles in rodent heart failure (HF) models and an acceptable safety profile in preclinical toxicology studies, improving cardiac function and useful for HF disease research.
Smiles
C(OCC)C=1N(C(O)=C(C(=O)N2C[C@H](CC2)C3=CC=CC=C3)C(=O)N1)C4=C(OC)C=CC=C4OC
Molecular Formula
C26H29N3O6
Molecular Weight
479.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
VAng-Lsx09913-500gEcoli 500 µg (E. coli)
Recombinant Shigella Sonnei murD Protein (aa 1-438)
Sign In for Pricing
View Details 
EK340647 96 Well
Human UBE2C (Ubiquitin Conjugating Enzyme E2C) ValidElisa Kit
Sign In for Pricing
View Details MBS1488470-01 0.05 mg
Rabbit anti-human Transcription factor p65 polyclonal Antibody, HRP conjugated
Sign In for Pricing
View Details