APJ receptor agonist 5
Product Specifications
CAS Number
2135514-20-2
Target
Others|||Apelin receptor
Related Pathways
Others|||GPCR/G Protein
Bioactivity
APJ receptor agonist 5 (compound 3) is a potent and orally active apelin receptor (APJ) agonist (EC 50: 0.4 nM) with excellent pharmacokinetic profiles in rodent heart failure (HF) models and an acceptable safety profile in preclinical toxicology studies, improving cardiac function and useful for HF disease research.
Smiles
C(OCC)C=1N(C(O)=C(C(=O)N2C[C@H](CC2)C3=CC=CC=C3)C(=O)N1)C4=C(OC)C=CC=C4OC
Molecular Formula
C26H29N3O6
Molecular Weight
479.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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