FLT3/CDK4-IN-1
Product Specifications
CAS Number
2762296-44-4
Target
Others, FLT, CDK
Related Pathways
Angiogenesis, Others, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint
Bioactivity
FLT3/CDK4-IN-1 is a highly selective, potent, orally active dual inhibitor of FLT3 (IC50: 7 nM) and CDK4 (IC50: 11 nM), demonstrating significant anti-tumor effects in vivo and anti-proliferative effects on certain cancer cells.
Smiles
C(C)(C)N1C=2C(=NC=C(C2)C3=NC(NC4=CC(F)=C(C=C4)N5CCN(CC)CC5)=NC=C3F)C=N1
Molecular Formula
C25H28F2N8
Molecular Weight
478.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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