FAK inhibitor 6
Product Specifications
CAS Number
2410056-27-6
Target
Others, FAK
Related Pathways
Angiogenesis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Others
Bioactivity
Compound 26F effectively optimizes enzyme inhibition (IC50 = 28.2 nM) while demonstrating relatively low cytotoxicity (IC50 = 3.32 μM) . It induces apoptosis in MDA-MB-231 cells in a dose-dependent manner and efficiently arrests these cells in the G0/G1 phase.
Smiles
N(C=1N=C2C(=CSC2=CN1)C3=C(OC)C=CC=C3)C4=CC(F)=C(C(NC5CCNCC5)=O)C=C4
Molecular Formula
C25H24FN5O2S
Molecular Weight
477.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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