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Bafetinib

Product Specifications

CAS Number

859212-16-1

Target

Autophagy, Apoptosis, Src, Bcr-Abl

Related Pathways

Autophagy, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Angiogenesis, Apoptosis

Purity

0.9968

Bioactivity

Bafetinib (INNO-406) (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5.8/19 nM), and no inhibition of the phosphorylation of the T315I mutant and less effective to c-Kit and PDGFR.

Smiles

CN(C)[C@H]1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cncnc3)c2)C1

Molecular Formula

C30H31F3N8O

Molecular Weight

576.62

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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