Bafetinib
Product Specifications
CAS Number
859212-16-1
Target
Autophagy|||Apoptosis|||Src|||Bcr-Abl
Related Pathways
Autophagy|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Angiogenesis|||Apoptosis
Purity
0.9968
Bioactivity
Bafetinib (INNO-406) (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5.8/19 nM), and no inhibition of the phosphorylation of the T315I mutant and less effective to c-Kit and PDGFR.
Smiles
CN(C)[C@H]1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cncnc3)c2)C1
Molecular Formula
C30H31F3N8O
Molecular Weight
576.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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