KS106
Product Specifications
CAS Number
2408477-50-7
Target
Dehydrogenase, Apoptosis
Related Pathways
Metabolism, Apoptosis
Purity
0.9931
Bioactivity
KS106 is a selective and potent ALDH inhibitor with antiproliferative and anticancer activity, inhibits ALDH1A1, ALDH2, and ALDH3A1 with IC50 of 334, 2137, and 360 nM, respectively.KS106 contributes to apoptosis, induces an increase in G2/M cell cycle arrest, and can be used to study melanoma and colon cancer.
Smiles
Br.NC(=N)SCc1ccc(CN2C(=O)C(=O)c3cc(ccc23)C(F)(F)F)cc1
Molecular Formula
C18H15BrF3N3O2S
Molecular Weight
474.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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