PI3Kδ/γ-IN-3
Product Specifications
CAS Number
2730151-31-0
Target
Others, PI3K, Apoptosis
Related Pathways
PI3K/Akt/mTOR signaling, Apoptosis, Others
Bioactivity
PI3Kδ/γ-IN-3 (Compound 58) is an orally active dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 16 nM), effective in inducing apoptosis of tumor cells and applicable to B-cell malignant tumor studies.
Smiles
O=C1N(C(=NC=2C1=C(Cl)C=CC2)[C@H]3N([C@@H](C)CC3)C=4C(C#N)=C(N)N=C(N)N4)C=5C=CC=NC5
Molecular Formula
C23H20ClN9O
Molecular Weight
473.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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