What is the catalog number for Ivaltinostat formic?

The catalog number for Ivaltinostat formic is T63074.

What sizes are available for Ivaltinostat formic?

Ivaltinostat formic is available in the following size(s): 10 mg, 25 mg.

How many pack sizes does Ivaltinostat formic come in?

Ivaltinostat formic is available in 2 different pack sizes.

Is Ivaltinostat formic in stock?

Ivaltinostat formic is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ivaltinostat formic?

Ivaltinostat formic is manufactured by Molfinity.

What is the estimated delivery time for Ivaltinostat formic?

Estimated delivery time for Ivaltinostat formic is approximately 10 business day(s), depending on your location.

Ivaltinostat formic

Product Specifications

Target

Others, MDM-2/p53, Apoptosis, HDAC

Related Pathways

Chromatin/Epigenetic, Apoptosis, DNA Damage/DNA Repair, Others

Bioactivity

Ivaltinostat (CG-200745) formic is an orally active pan-HDAC inhibitor with an isohydroxamic acid component that binds zinc at the bottom of the catalytic pocket. Ivaltinostat formic inhibits the deacetylation of histone H3 and tubulin, promotes p53 accumulation, induces p53-dependent transactivation, and enhances MDM2 and p21 (Waf1/Cip1) protein expression. It increases the sensitivity of Gemcitabine-resistant cells to Gemcitabine and 5-Fluorouracil (5-FU), induces apoptosis, and has antitumor effects.