Rucaparib tartrate
Product Specifications
CAS Number
773059-22-6
Target
Others, PARP
Related Pathways
Others, Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
Rucaparib (AG014699) tartrate is an orally active inhibitor of PARP proteins (PARP-1, PARP-2, and PARP-3) and acts on PARP-1 (Ki: 1.4 nM) . It is also a hexose hexaphosphate dehydrogenase (H6PD) inhibitor and has potential for use in the study of destructive resistant prostate cancer (CRPC) .
Smiles
O[C@H]([C@@H](O)C(O)=O)C(O)=O.CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23
Molecular Formula
C23H24FN3O7
Molecular Weight
473.457
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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