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FLT3-IN-14

Product Specifications

CAS Number

2620551-45-1

Target

FLT, Apoptosis, Others

Related Pathways

Apoptosis, Others, Angiogenesis, Tyrosine Kinase/Adaptors

Bioactivity

FLT3-IN-14 is a potent inhibitor of FLT3, targeting FLT3-WT (IC50: 5.6 nM) and FLT3-ITD (IC50: 1.4 nM) . It inhibits FLT3 (Y591) phosphorylation, arrests the cell cycle in the G1 phase, and induces apoptosis.

Smiles

N(C(NC=1C=C(C(C)(C)C)ON1)=O)C2=CC=C(C3=CN4C=5C=6C(CCC5SC4=N3)=CNC6)C=C2

Molecular Formula

C25H24N6O2S

Molecular Weight

472.56

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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