JH-XVII-10
Product Specifications
Target
Others, Apoptosis, DYRK
Related Pathways
Cell Cycle/Checkpoint, Apoptosis, Others, Tyrosine Kinase/Adaptors
Bioactivity
JH-XVII-10 is a selective, orally active and potent inhibitor of DYRK1A (IC50: 3 nM) and DYRK1B (IC50: 5 nM) .JH-XVII-10 exhibits antitumor effects in squamous cell carcinoma of the neck (HNSCC) cell lines.
Molecular Formula
C21H16F4N8O
Molecular Weight
472.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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