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JH-XVII-10

Product Specifications

Target

Others, Apoptosis, DYRK

Related Pathways

Cell Cycle/Checkpoint, Apoptosis, Others, Tyrosine Kinase/Adaptors

Bioactivity

JH-XVII-10 is a selective, orally active and potent inhibitor of DYRK1A (IC50: 3 nM) and DYRK1B (IC50: 5 nM) .JH-XVII-10 exhibits antitumor effects in squamous cell carcinoma of the neck (HNSCC) cell lines.

Molecular Formula

C21H16F4N8O

Molecular Weight

472.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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