SOS1-IN-6

2751718-88-2

Others|||Ras

MAPK|||GPCR/G Protein|||Others

SOS1-IN-6 (compound 33-P1) is a potent inhibitor of SOS1, exhibiting an IC50 of 14.9 nM on SOS1-G12D and 73.3 nM on SOS1-G12V.

N([C@H](C)C1=C(F)C(C(F)F)=CC=C1)C2=C3C(C4=C(C(=C3)[C@@H]5CC[C@@H](O)CC5)OCC4)=NC(C)=N2

C26H28F3N3O2

471.51

Cool pack

-20°C