Izilendustat hydrochloride
Product Specifications
CAS Number
1303513-80-5
Target
Others, HIF/HIF Prolyl-Hydroxylase
Related Pathways
Others, Metabolism, Chromatin/Epigenetic
Bioactivity
Izilendustat (hydrochloride) is a potent inhibitor of prolyl hydroxylase that stabilizes hypoxia-inducible factor-1 alpha (HIF-1α) and hypoxia-inducible factor-2 (HIF-2), with potential applications in HIF-1α-related diseases, including peripheral vascular disease (PVD), heart failure, coronary artery disease (CAD), ischaemia, anaemia, colitis, and other inflammatory bowel diseases.
Smiles
Cl.CC(C)(C)OC(=O)N1CCN(Cc2ccn(Cc3ccc(Cl)cc3)c(=O)c2O)CC1
Molecular Formula
C22H29Cl2N3O4
Molecular Weight
470.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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