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Lonafarnib

Product Specifications

CAS Number

193275-84-2

Target

Autophagy|||Ras|||Raf|||Kras|||Transferase

Related Pathways

MAPK|||Autophagy|||Metabolism|||GPCR/G Protein

Purity

0.9994

Bioactivity

Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM) .

Smiles

NC(=O)N1CCC(CC(=O)N2CCC(CC2)[C@H]2c3ncc(Br)cc3CCc3cc(Cl)cc(Br)c23)CC1

Molecular Formula

C27H31Br2ClN4O2

Molecular Weight

638.82

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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