TM-1

Product Specifications

CAS Number

921099-13-0

Target

Others|||Dehydrogenase

Related Pathways

Metabolism|||Others

Bioactivity

TM-1 is a potent pyruvate dehydrogenase kinase (PDHK) inhibitor that inhibits the activity of PDHK1 (IC50: 2.97 ?M) and PDHK2 (IC50: 5.2 ?M) . TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation and inhibits cancer cell proliferation.

Smiles

COc1ccc(cc1OC)-c1c(C)c2ccc(OCCN3CCN(CCO)CC3)cc2oc1=O

Molecular Formula

C26H32N2O6

Molecular Weight

468.54

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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