TM-1
Product Specifications
CAS Number
921099-13-0
Target
Others|||Dehydrogenase
Related Pathways
Metabolism|||Others
Bioactivity
TM-1 is a potent pyruvate dehydrogenase kinase (PDHK) inhibitor that inhibits the activity of PDHK1 (IC50: 2.97 ?M) and PDHK2 (IC50: 5.2 ?M) . TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation and inhibits cancer cell proliferation.
Smiles
COc1ccc(cc1OC)-c1c(C)c2ccc(OCCN3CCN(CCO)CC3)cc2oc1=O
Molecular Formula
C26H32N2O6
Molecular Weight
468.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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