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MA242 free base

Product Specifications

CAS Number

1049704-17-7

Target

MDM-2/p53|||Apoptosis|||Others

Related Pathways

Apoptosis|||Others

Bioactivity

MA242 free base is a specific dual inhibitor of MDM2 and NFAT1 that induces apoptosis in pancreatic cancer cell lines. It binds directly to MDM2 and NFAT1 with high affinity, induces their protein degradation, and inhibits NFAT1-mediated MDM2 transcription.

Smiles

S(=O)(=O)(N1C2=C3C(=C1)CCN=C3C=C(NCC4=CC=C(Cl)C=C4)C2=O)C5=CC=C(C)C=C5

Molecular Formula

C24H20ClN3O3S

Molecular Weight

465.95

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/4B90F9B5-15FF-4F14-A826-8B9FD98552D5/T62977

Available Sizes

Curated Selection

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