PDE4-IN-6
Product Specifications
Target
Others, PDE
Related Pathways
Others, Metabolism
Bioactivity
PDE4-IN-6 is a safe, potent and moderately selective inhibitor of PDE4, acting on PDE4B (IC50: 0.125 μM) and PDE4D (IC50: 0.43 μM) . PDE4-IN-6 is able to down-regulate TNF-α and IL-6 expression levels, exhibits anti-inflammatory and anti-arthritic effects, and has potent immunomodulatory activity. PDE4-IN-6 has potential for anti-rheumatoid arthritis studies.
Molecular Formula
C25H20FNO5S
Molecular Weight
465.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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