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PDE4-IN-6

Product Specifications

Target

Others, PDE

Related Pathways

Others, Metabolism

Bioactivity

PDE4-IN-6 is a safe, potent and moderately selective inhibitor of PDE4, acting on PDE4B (IC50: 0.125 μM) and PDE4D (IC50: 0.43 μM) . PDE4-IN-6 is able to down-regulate TNF-α and IL-6 expression levels, exhibits anti-inflammatory and anti-arthritic effects, and has potent immunomodulatory activity. PDE4-IN-6 has potential for anti-rheumatoid arthritis studies.

Molecular Formula

C25H20FNO5S

Molecular Weight

465.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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