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IRAK4-IN-18

Product Specifications

Target

IRAK, Others

Related Pathways

Immunology/Inflammation, NF-κB, Others

Bioactivity

IRAK4-IN-18 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) (IC50: 15 nM) . It inhibits LPS-induced IL23 production in THP and DC cells and blocks the development of arthritis in rats, making it useful for studying arthritic diseases.

Molecular Formula

C24H25FN6O3

Molecular Weight

464.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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