IRAK4-IN-18
Product Specifications
Target
IRAK|||Others
Related Pathways
Immunology/Inflammation|||NF-?B|||Others
Bioactivity
IRAK4-IN-18 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) (IC50: 15 nM) . It inhibits LPS-induced IL23 production in THP and DC cells and blocks the development of arthritis in rats, making it useful for studying arthritic diseases.
Molecular Formula
C24H25FN6O3
Molecular Weight
464.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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