Aurora A/PKC-IN-1
Product Specifications
CAS Number
2143100-98-3
Target
Others, PKC, Aurora Kinase
Related Pathways
Others, Cytoskeletal Signaling, Chromatin/Epigenetic, Cell Cycle/Checkpoint
Bioactivity
Aurora A/PKC-IN-1 (Compound 2e) is a potent dual inhibitor of Aurora A (AurA) and PKC (α, β1, β2, θ), exhibiting inhibitory activity on AurA (IC50: 6.9 nM) and PKCα (IC50: 16.9 nM), and demonstrating anti-proliferative and anti-metastatic effects on breast cancer cells.
Smiles
O=C1N([Se]C=2C1=CC=CC2)C3=NC(NC4CC[Se]C4)=C5C(=N3)N=CN5
Molecular Formula
C16H14N6OSe2
Molecular Weight
464.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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