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ZLHQ-5f

Product Specifications

Target

CDK|||Topoisomerase|||Others|||Apoptosis

Related Pathways

Others|||Apoptosis|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

Bioactivity

ZLHQ-5f is a dual inhibitor of CDK2 and Topo I, acting on CDK2/CycA2 (IC50: 0.145 ?M) . ZLHQ-5f has a good safety profile by blocking the cell cycle of HCT116 cells in S phase and inducing apoptosis.

Molecular Formula

C28H25N5O2

Molecular Weight

463.53

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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