RLX-33
Product Specifications
CAS Number
2784577-71-3
Target
RXFP receptor, ERK
Related Pathways
MAPK, GPCR/G Protein
Purity
0.9989
Bioactivity
RLX-33 is a potent and selective antagonist of relaxin family peptide 3 (RXFP3) that crosses the blood-brain barrier and also blocks relaxin 3-induced ERK1/2 phosphorylation. RLX-33 can block the increase in food intake induced by the RXFP3 selective agonist R3/I5 in rats.RLX-33 can be used to study the metabolic syndrome.
Smiles
N(C(=O)C1CN(CC2=CC=CO2)C(=O)C1)C3=CC=C(C4=NC(=NO4)C5=CC=C(Cl)C=C5)C=C3
Molecular Formula
C24H19ClN4O4
Molecular Weight
462.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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