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ZYF0033

Product Specifications

CAS Number

2380300-79-6

Target

MAPK, Others

Related Pathways

MAPK, Others

Purity

0.997

Bioactivity

ZYF0033 is an orally effective small molecule inhibitor of hematopoietic progenitor kinase 1 (HPK1) that inhibits the phosphorylation of MBP proteins.HPK1-IN-22 promotes anticancer immune responses by decreasing the phosphorylation of SLP76 (serine 76), and has the potential to inhibit tumor growth and mediate immune responses.

Smiles

OC(C#CC1=CC=CC(=C1)COC=2C=C(C=NC2N)C=3SC(=NC3)C4CCN(C)CC4)(C)C

Molecular Formula

C26H30N4O2S

Molecular Weight

462.61

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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