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MIR002

Product Specifications

CAS Number

2217671-64-0

Target

Apoptosis, DNA/RNA Synthesis, Others, HDAC

Related Pathways

Chromatin/Epigenetic, Cell Cycle/Checkpoint, Apoptosis, DNA Damage/DNA Repair, Others

Bioactivity

MIR002 is a potent, orally active dual inhibitor of DNA polymerase α (POLA1) and HDAC 11 with significant in vivo antitumor activity. p53 acetylation, p21 activation, cell cycle arrest in G1/S phase, and apoptosis induction.

Smiles

O(CC(NO)=O)C1=C(C23CC4CC(C2)CC(C3)C4)C=C(C=C1)C5=CC=C(/C=C/C(O)=O)C=C5

Molecular Formula

C27H29NO5

Molecular Weight

447.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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