MIR002
Product Specifications
CAS Number
2217671-64-0
Target
Apoptosis, DNA/RNA Synthesis, Others, HDAC
Related Pathways
Chromatin/Epigenetic, Cell Cycle/Checkpoint, Apoptosis, DNA Damage/DNA Repair, Others
Bioactivity
MIR002 is a potent, orally active dual inhibitor of DNA polymerase α (POLA1) and HDAC 11 with significant in vivo antitumor activity. p53 acetylation, p21 activation, cell cycle arrest in G1/S phase, and apoptosis induction.
Smiles
O(CC(NO)=O)C1=C(C23CC4CC(C2)CC(C3)C4)C=C(C=C1)C5=CC=C(/C=C/C(O)=O)C=C5
Molecular Formula
C27H29NO5
Molecular Weight
447.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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