PI3K/HDAC-IN-2
Product Specifications
CAS Number
2361418-65-5
Target
Others|||PI3K|||HDAC
Related Pathways
Others|||PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair|||Chromatin/Epigenetic
Bioactivity
PI3K/HDAC-IN-2 is a potent dual PI3K/HDAC inhibitor with IC50 values of 226 nM for PI3K?, 279 nM for PI3K?, 467 nM for PI3K?, 29 nM for PI3K?, and 1.3 nM for HDAC1. PI3K/HDAC-IN-2 is selective for PI3K? and class I and IIb HDACs, exhibiting significant anticancer effects.
Smiles
O(CCN(C)C=1N=CC(C(NO)=O)=CN1)C=2C3=C(C=C(C2)C=4C=CC(OC)=NC4)C(C)=NC=N3
Molecular Formula
C23H23N7O4
Molecular Weight
461.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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