TAS-117 hydrochloride
Product Specifications
Target
Others, Akt, Apoptosis, Autophagy
Related Pathways
PI3K/Akt/mTOR signaling, Autophagy, Others, Cytoskeletal Signaling, Apoptosis
Bioactivity
TAS-117 hydrochloride is a selective, potent, orally active allosteric Akt inhibitor, acting on Akt1 (IC50: 4.8 nM), Akt2 (IC50: 1.6 nM) and Akt3 (IC50: 44 nM) . TAS-117 hydrochloride stimulates anti-myeloma activity, enhances lethal endoplasmic reticulum stress induced by proteasome inhibition, and can induce apoptosis and autophagy.
Molecular Formula
C26H25ClN4O2
Molecular Weight
460.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
134122-ML650 100 µL
Syncollin (SYCN, SYL, Insulin Synthesis-associated Protein 1, INSSA1) (MaxLight 650)
Sign In for Pricing
View Details 
