Tau-aggregation and neuroinflammation-IN-1
Product Specifications
CAS Number
2175953-98-5
Target
NO Synthase, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Immunology/Inflammation
Purity
>99.99%
Bioactivity
Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-length tau protein aggregates. It has anti-inflammatory activity, reduces NO release, exhibits low cytotoxicity against LSP-stimulated BV2 cells, and reverses okadaic acid-induced memory impairment in rats.
Smiles
C[C@@]12C=3C(OC1=CC4=C(C2=O)C(C)=NN4C5=CC=C(C(O)=O)C=C5)=C(C(C)=O)C(O)=C(C)C3O
Molecular Formula
C25H20N2O7
Molecular Weight
460.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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