Glucosylceramide synthase-IN-1
Product Specifications
CAS Number
2601393-20-6
Target
Others, Transferase
Related Pathways
Others, Metabolism
Bioactivity
Glucosylceramide synthase-IN-1 (T-036) is a potent, orally active, blood-brain barrier permeable glucosylceramide synthase (GCS) inhibitor, acting on human GCS (IC50: 31 nM) and mouse GCS (IC50: 51 nM), and can be used to study Gaucher disease.
Smiles
CC(C)(O)c1ccc(cc1)N1Cc2c(ccnc2-c2ccc(F)cc2OCC(F)(F)F)C1=O
Molecular Formula
C24H20F4N2O3
Molecular Weight
460.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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