LRRK2-IN-6
Product Specifications
Target
Others, LRRK2
Related Pathways
Others, Autophagy
Bioactivity
LRRK2-IN-6 (compound 22) is an orally active, selective leucine-rich repeat protein kinase 2 (LRRK2) inhibitor with blood-brain barrier permeability, inhibiting GS LRRK2 (IC50: 4.6 μM) and WT LRRK2 (IC50: 49 μM) . LRRK2-IN-6 exhibited inhibitory effects on the autophosphorylation of LRRK2 at Ser1292 and Ser925.
Molecular Formula
C23H24F2N4O2S
Molecular Weight
458.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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