FLT3/ITD-IN-4
Product Specifications
CAS Number
2278278-04-7
Target
FLT, c-RET, MAPK, Others, CDK
Related Pathways
Apoptosis, MAPK, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Angiogenesis, Others
Bioactivity
FLT3/ITD-IN-4 (Compound 16) is a selective inhibitor of FLT3 internal tandem repeat mutations (FLT3-ITD) with an IC50 of 2.3 nM and is applicable for studying acute myeloid leukemia.
Smiles
C(=O)(C1=CC=2C(O1)=CC=C(NC(NC=3C=C(C(C)(C)C)ON3)=O)C2)C=4NC=5C(C4)=CC(O)=CC5
Molecular Formula
C25H22N4O5
Molecular Weight
458.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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