YM-341619
Product Specifications
CAS Number
643082-52-4
Target
Others|||STAT
Related Pathways
Others|||JAK/STAT signaling|||Stem Cells
Bioactivity
YM-341619 (AS1617612) is a potent, orally active STAT6 inhibitor (IC50: 0.70 nM) that inhibits IL-4-induced Th2 differentiation in mouse splenic T cells with an IC50 value of 0.28 nM, without affecting Th1 cell differentiation. YM-341619 holds potential for research into allergic diseases, such as allergic asthma.
Smiles
NC(=O)c1cnc(Nc2ccc(cc2)N2CCOCC2)nc1NCc1c(F)ccc(F)c1F
Molecular Formula
C22H21F3N6O2
Molecular Weight
458.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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