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UNC9994 hydrochloride

Product Specifications

CAS Number

2108826-33-9

Target

5-HT Receptor|||Dopamine Receptor|||Arrestin|||Others

Related Pathways

Neuroscience|||GPCR/G Protein|||Others

Bioactivity

UNC9994 hydrochloride is a functionally selective, ?-arrestin-biased dopamine D2 receptor (D2R) agonist (Ki: 79 nM) that selectively activates ?-arrestin recruitment and signal transduction. UNC9994 hydrochloride is a Gi-regulated antagonist of cAMP production and a partial agonist of the D2R/?-arrestin-2 interaction, exhibiting psychostimulatory effects.

Smiles

Cl.Clc1cccc(C2CCN(CCCOc3ccc4scnc4c3)CC2)c1Cl

Molecular Formula

C21H23Cl3N2OS

Molecular Weight

457.84

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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