GSK-690693
Product Specifications
CAS Number
937174-76-0
Target
PKC, Serine Protease, Akt, Autophagy, AMPK
Related Pathways
Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Proteases/Proteasome, Autophagy
Purity
>99.99%
Bioactivity
GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.
Smiles
CCn1c(nc2c(ncc(OC[C@H]3CCCNC3)c12)C#CC(C)(C)O)-c1nonc1N
Molecular Formula
C21H27N7O3
Molecular Weight
425.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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