Wortmannin
Product Specifications
CAS Number
19545-26-7
Target
Antibiotic, PI3K, Serine/threonin kinase, Autophagy, ATM/ATR, PLK, DNA-PK
Related Pathways
Metabolism, Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling, Autophagy, DNA Damage/DNA Repair, Microbiology/Virology
Purity
0.9977
Bioactivity
Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible. Wortmannin is also an inhibitor of PlK1 and PlK3 (IC50=5.8/48 nM) that blocks autophagy.
Smiles
C[C@@]12C3=C([C@]4([C@](C)(C[C@H]3OC(C)=O)C(=O)CC4)[H])C(=O)C5=C1C(C(=O)O[C@@H]2COC)=CO5
Molecular Formula
C23H24O8
Molecular Weight
428.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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