Antitumor agent-77

Product Specifications

CAS Number

9007-83-4

Target

Others|||Apoptosis|||Bcl-2 Family|||Ferroptosis|||COX

Related Pathways

Apoptosis|||Others|||Immunology/Inflammation|||Neuroscience

Bioactivity

Antitumor agent-77 inhibits the growth and migration of cancer cells and has anticancer effects. antitumor agent-77 inhibits GPx-4 and enhances COX2-induced iron sagging. antitumor agent-77 activates the intrinsic apoptotic pathway (Bax-Bcl-2-caspase-3) in tumor cells and prevents tumor cell epithelialization. Antitumor agent-77 activates the tumour cell intrinsic apoptotic pathway (Bax-Bcl-2-caspase-3) and blocks the epithelial mesenchymal transition (EMT) process.