RdRP-IN-4
Product Specifications
Target
Others|||Influenza Virus
Related Pathways
Others|||Microbiology/Virology
Bioactivity
RdRP-IN-4 (compound 11q) is an arylbenzohydrazide analogue, an orally active inhibitor of influenza A virus RNA-dependent RNA polymerase (RdRp) that directly binds the PB1 subunit of RdRp. RdRP-IN-4 inhibited H1N1 (A/PR/8/34) Flu A and Flu B strains (B/Lee/1940) in a dose-dependent manner with EC50 values of 53 nM and 20 nM, respectively. RdRP-IN-4 had a significant antiviral effect in infected mice.
Molecular Formula
C17H17Br2N3O2
Molecular Weight
455.14
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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