Trk-IN-9
Product Specifications
CAS Number
2758623-12-8
Target
Apoptosis, Trk receptor
Related Pathways
Tyrosine Kinase/Adaptors, Apoptosis
Purity
0.9815
Bioactivity
Trk-IN-9 (Compound 12) is a potent inhibitor of TRK that inhibits the proliferation of Km-12 cell lines and induces apoptosis in a concentration-dependent manner. It also inhibits TRK phosphorylation and blocks downstream pathways, showing potential for NTRK fusion cancer research.
Smiles
N(C=1N=C(NCC2=CC(F)=CC=C2)C(Cl)=CN1)C3=CC(C(N[C@@H]4CCCNC4)=O)=CC=C3
Molecular Formula
C23H24ClFN6O
Molecular Weight
454.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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