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JH-XIV-68-3

Product Specifications

CAS Number

2426628-52-4

Target

DYRK, Others

Related Pathways

Cell Cycle/Checkpoint, Others, Tyrosine Kinase/Adaptors

Bioactivity

JH-XIV-68-3 is a selective inhibitor of the DYRK1A/B macrocycle, acting specifically on DYRK1A and DYRK1B in biochemical and cellular assays, and exhibiting antitumor effects in head and neck squamous cell carcinoma (HNSCC) cell lines.

Smiles

C(#N)C1=C2C(=NN1C)N(C)C(=O)CCCN3C=C(C=4C5=CC2=CN=C5NC4)C(C(F)(F)F)=N3

Molecular Formula

C21H17F3N8O

Molecular Weight

454.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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