JH-XIV-68-3
Product Specifications
CAS Number
2426628-52-4
Target
DYRK, Others
Related Pathways
Cell Cycle/Checkpoint, Others, Tyrosine Kinase/Adaptors
Bioactivity
JH-XIV-68-3 is a selective inhibitor of the DYRK1A/B macrocycle, acting specifically on DYRK1A and DYRK1B in biochemical and cellular assays, and exhibiting antitumor effects in head and neck squamous cell carcinoma (HNSCC) cell lines.
Smiles
C(#N)C1=C2C(=NN1C)N(C)C(=O)CCCN3C=C(C=4C5=CC2=CN=C5NC4)C(C(F)(F)F)=N3
Molecular Formula
C21H17F3N8O
Molecular Weight
454.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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