Pexidartinib hydrochloride
Product Specifications
CAS Number
2040295-03-0
Target
Apoptosis, c-Fms, c-Kit
Related Pathways
Apoptosis, Tyrosine Kinase/Adaptors
Purity
0.9988
Bioactivity
Pexidartinib hydrochloride (PLX-3397 HCl) is a selective, orally active, ATP-competitive CSF1R/M-CSFR inhibitor and c-Kit inhibitor with IC50 values of 20 and 10 nM, respectively, capable of inducing cancer cell apoptosis.
Smiles
Cl.FC(F)(F)C1=NC=C(C=C1)CNC2=NC=C(C=C2)CC3=CNC=4N=CC(Cl)=CC43
Molecular Formula
C20H16Cl2F3N5
Molecular Weight
454.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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