Pexidartinib hydrochloride

Product Specifications

CAS Number

2040295-03-0

Target

Apoptosis, c-Fms, c-Kit

Related Pathways

Apoptosis, Tyrosine Kinase/Adaptors

Purity

0.9988

Bioactivity

Pexidartinib hydrochloride (PLX-3397 HCl) is a selective, orally active, ATP-competitive CSF1R/M-CSFR inhibitor and c-Kit inhibitor with IC50 values of 20 and 10 nM, respectively, capable of inducing cancer cell apoptosis.

Smiles

Cl.FC(F)(F)C1=NC=C(C=C1)CNC2=NC=C(C=C2)CC3=CNC=4N=CC(Cl)=CC43

Molecular Formula

C20H16Cl2F3N5

Molecular Weight

454.28

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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