PI3K-IN-35
Product Specifications
CAS Number
2458163-99-8
Target
Others, PI3K, Apoptosis
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling, Others
Bioactivity
PI3K-IN-35 (Compound 6l) is a highly selective inhibitor of PI3K, targeting PI3K-α (IC50: 13.98 μM), PI3K-β (IC50: 7.22 μM), and PI3K-δ (IC50: 10.94 μM) . It blocks the cell cycle in the G2/M phase and induces apoptosis, making it useful for studying leukemia.
Smiles
C(#N)C=1C(=NC(NN=CC=2C=3C(NC2)=CC=CC3)=NC1N4CCOCC4)C5=CC=C(OC)C=C5
Molecular Formula
C25H23N7O2
Molecular Weight
453.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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