Doramapimod
Product Specifications
CAS Number
285983-48-4
Target
Autophagy, Raf, p38 MAPK
Related Pathways
MAPK, Autophagy
Purity
0.9965
Bioactivity
Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.
Smiles
Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)c2ccccc12)C(C)(C)C
Molecular Formula
C31H37N5O3
Molecular Weight
527.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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