RIPK1-IN-11
Product Specifications
CAS Number
2173557-02-1
Target
Others, RIP kinase
Related Pathways
NF-κB, Apoptosis, Others
Bioactivity
RIPK1-IN-11 is an orally active RIPK1 inhibitor with a Kd value of 9.2 nM and an IC50 value of 67 nM. RIPK1-IN-11 inhibits necrosis in human and mouse cells and exhibits anti-inflammatory effects.
Smiles
N(C(=O)C1CC1)C=2SC=3C(N2)=CC=C(C3)C=4C=C(NC(OC5CCOCC5)=O)C(C)=NC4
Molecular Formula
C23H24N4O4S
Molecular Weight
452.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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