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RIPK1-IN-11

Product Specifications

CAS Number

2173557-02-1

Target

Others, RIP kinase

Related Pathways

NF-κB, Apoptosis, Others

Bioactivity

RIPK1-IN-11 is an orally active RIPK1 inhibitor with a Kd value of 9.2 nM and an IC50 value of 67 nM. RIPK1-IN-11 inhibits necrosis in human and mouse cells and exhibits anti-inflammatory effects.

Smiles

N(C(=O)C1CC1)C=2SC=3C(N2)=CC=C(C3)C=4C=C(NC(OC5CCOCC5)=O)C(C)=NC4

Molecular Formula

C23H24N4O4S

Molecular Weight

452.53

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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